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Computational Analysis of LOX1 Inhibition Identifies Descriptors Responsible for Binding Selectivity
[Image: see text] Lipoxygenases are a family of cytosolic, peripheral membrane enzymes, which catalyze the hydroperoxidation of polyunsaturated fatty acids and are implicated in the pathogenesis of major human diseases. Over the years, a substantial number of scientific reports have introduced inhib...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044675/ https://www.ncbi.nlm.nih.gov/pubmed/30023828 http://dx.doi.org/10.1021/acsomega.7b01622 |