Effective Theranostic Cyanine for Imaging of Amyloid Species in Vivo and Cognitive Improvements in Mouse Model

[Image: see text] We report herein an investigation of carbazole-based cyanine, (E)-4-(2-(9-(2-(2-methoxyethoxy)ethyl)-9H-carbazol-3-yl)-vinyl)-1-methyl-quinolin-1-iumiodide (SLM), as an effective theranostic agent for Alzheimer’s disease (AD). This cyanine exhibited desirable multifunctional and bi...

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Detalles Bibliográficos
Autores principales: Li, Yinhui, Chen, Chen, Xu, Di, Poon, Chung-Yan, Ho, See-Lok, Zheng, Rui, Liu, Qiong, Song, Guoli, Li, Hung-Wing, Wong, Man Shing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044748/
https://www.ncbi.nlm.nih.gov/pubmed/30023962
http://dx.doi.org/10.1021/acsomega.8b00475

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