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Empirical Valence Bond Simulations Suggest a Direct Hydride Transfer Mechanism for Human Diamine Oxidase

[Image: see text] Diamine oxidase (DAO) is an enzyme involved in the regulation of cell proliferation and the immune response. This enzyme performs oxidative deamination in the catabolism of biogenic amines, including, among others, histamine, putrescine, spermidine, and spermine. The mechanistic de...

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Detalles Bibliográficos
Autores principales:	Maršavelski, Aleksandra, Petrović, Dušan, Bauer, Paul, Vianello, Robert, Kamerlin, Shina Caroline Lynn
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2018
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044848/ https://www.ncbi.nlm.nih.gov/pubmed/30023875 http://dx.doi.org/10.1021/acsomega.8b00346

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