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Mapping Putative B-Cell Zika Virus NS1 Epitopes Provides Molecular Basis for Anti-NS1 Antibody Discrimination between Zika and Dengue Viruses
[Image: see text] B-cell epitope sequences from Zika virus (ZIKV) NS1 protein have been identified using epitope prediction tools. Mapping these sequences onto the NS1 surface reveals two major conformational epitopes and a single linear one. Despite an overall average sequence identity of ca. 55% b...
Autores principales: | Freire, Marjorie C. L. C., Pol-Fachin, Laércio, Coêlho, Danilo F., Viana, Isabelle F. T., Magalhães, Tereza, Cordeiro, Marli T., Fischer, Nico, Loeffler, Felix F., Jaenisch, Thomas, Franca, Rafael F., Marques, Ernesto T. A., Lins, Roberto D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044859/ https://www.ncbi.nlm.nih.gov/pubmed/30023708 http://dx.doi.org/10.1021/acsomega.7b00608 |
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