FIKK Kinase, a Ser/Thr Kinase Important to Malaria Parasites, Is Inhibited by Tyrosine Kinase Inhibitors

[Image: see text] A relatively high-affinity inhibitor of FIKK kinase from the malaria parasite Plasmodium vivax was identified by in vitro assay of recombinant kinase. The FIKK kinase family is unique to parasitic organisms of the Apicomplexan order and has been shown to be critical in malaria para...

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Detalles Bibliográficos
Autores principales: Lin, Benjamin C., Harris, Darcy R., Kirkman, Lucy M. D., Perez, Astrid M., Qian, Yiwen, Schermerhorn, Janse T., Hong, Min Y., Winston, Dennis S., Xu, Lingyin, Brandt, Gabriel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044879/
https://www.ncbi.nlm.nih.gov/pubmed/30023525
http://dx.doi.org/10.1021/acsomega.7b00997

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