Cargando…

Improving Antibacterial Activity and Biocompatibility of Bioinspired Electrospinning Silk Fibroin Nanofibers Modified by Graphene Oxide

[Image: see text] In this article, the silk fibroin (SF)/graphene oxide (GO)-blended nanofibers with one bioinspired nanostructure are fabricated via electrospinning. The morphology, chemical structure, antibacterial activity, and biocompatibility of the blending nanofibers are investigated. The res...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Shu-Dong, Ma, Qian, Wang, Ke, Chen, Hong-Wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044913/
https://www.ncbi.nlm.nih.gov/pubmed/30023780
http://dx.doi.org/10.1021/acsomega.7b01210
_version_ 1783339571263569920
author Wang, Shu-Dong
Ma, Qian
Wang, Ke
Chen, Hong-Wu
author_facet Wang, Shu-Dong
Ma, Qian
Wang, Ke
Chen, Hong-Wu
author_sort Wang, Shu-Dong
collection PubMed
description [Image: see text] In this article, the silk fibroin (SF)/graphene oxide (GO)-blended nanofibers with one bioinspired nanostructure are fabricated via electrospinning. The morphology, chemical structure, antibacterial activity, and biocompatibility of the blending nanofibers are investigated. The results indicate that GO plays an important role in preparing the distinctive bioinspired structure. The antibacterial activity and in vivo cell culture test demonstrate that blending of GO could improve the antibacterial activity and biocompatibility of SF nanofibers. The blended nanofibers developed in this study may have considerable potential for wound dressing applications.
format Online
Article
Text
id pubmed-6044913
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher American Chemical Society
record_format MEDLINE/PubMed
spelling pubmed-60449132018-07-16 Improving Antibacterial Activity and Biocompatibility of Bioinspired Electrospinning Silk Fibroin Nanofibers Modified by Graphene Oxide Wang, Shu-Dong Ma, Qian Wang, Ke Chen, Hong-Wu ACS Omega [Image: see text] In this article, the silk fibroin (SF)/graphene oxide (GO)-blended nanofibers with one bioinspired nanostructure are fabricated via electrospinning. The morphology, chemical structure, antibacterial activity, and biocompatibility of the blending nanofibers are investigated. The results indicate that GO plays an important role in preparing the distinctive bioinspired structure. The antibacterial activity and in vivo cell culture test demonstrate that blending of GO could improve the antibacterial activity and biocompatibility of SF nanofibers. The blended nanofibers developed in this study may have considerable potential for wound dressing applications. American Chemical Society 2018-01-12 /pmc/articles/PMC6044913/ /pubmed/30023780 http://dx.doi.org/10.1021/acsomega.7b01210 Text en Copyright © 2018 American Chemical Society This is an open access article published under an ACS AuthorChoice License (http://pubs.acs.org/page/policy/authorchoice_termsofuse.html) , which permits copying and redistribution of the article or any adaptations for non-commercial purposes.
spellingShingle Wang, Shu-Dong
Ma, Qian
Wang, Ke
Chen, Hong-Wu
Improving Antibacterial Activity and Biocompatibility of Bioinspired Electrospinning Silk Fibroin Nanofibers Modified by Graphene Oxide
title Improving Antibacterial Activity and Biocompatibility of Bioinspired Electrospinning Silk Fibroin Nanofibers Modified by Graphene Oxide
title_full Improving Antibacterial Activity and Biocompatibility of Bioinspired Electrospinning Silk Fibroin Nanofibers Modified by Graphene Oxide
title_fullStr Improving Antibacterial Activity and Biocompatibility of Bioinspired Electrospinning Silk Fibroin Nanofibers Modified by Graphene Oxide
title_full_unstemmed Improving Antibacterial Activity and Biocompatibility of Bioinspired Electrospinning Silk Fibroin Nanofibers Modified by Graphene Oxide
title_short Improving Antibacterial Activity and Biocompatibility of Bioinspired Electrospinning Silk Fibroin Nanofibers Modified by Graphene Oxide
title_sort improving antibacterial activity and biocompatibility of bioinspired electrospinning silk fibroin nanofibers modified by graphene oxide
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044913/
https://www.ncbi.nlm.nih.gov/pubmed/30023780
http://dx.doi.org/10.1021/acsomega.7b01210
work_keys_str_mv AT wangshudong improvingantibacterialactivityandbiocompatibilityofbioinspiredelectrospinningsilkfibroinnanofibersmodifiedbygrapheneoxide
AT maqian improvingantibacterialactivityandbiocompatibilityofbioinspiredelectrospinningsilkfibroinnanofibersmodifiedbygrapheneoxide
AT wangke improvingantibacterialactivityandbiocompatibilityofbioinspiredelectrospinningsilkfibroinnanofibersmodifiedbygrapheneoxide
AT chenhongwu improvingantibacterialactivityandbiocompatibilityofbioinspiredelectrospinningsilkfibroinnanofibersmodifiedbygrapheneoxide