Iminosugars Spiro-Linked with Morpholine-Fused 1,2,3-Triazole: Synthesis, Conformational Analysis, Glycosidase Inhibitory Activity, Antifungal Assay, and Docking Studies

[Image: see text] Synthesis of iminosugars 1, 2, 3a, and 4a and N-alkyl (ethyl, butyl, hexyl, octyl, decyl, and dodecyl) derivatives 3b–g and 4b–g spiro-linked with morpholine-fused 1,2,3-triazole is described. Conformation of the piperidine ring in each spiro-iminosugar was evaluated by (1)H NMR sp...

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Detalles Bibliográficos
Autores principales: Chavan, Shrawan R., Gavale, Kishor S., Khan, Ayesha, Joshi, Rakesh, Kumbhar, Navanath, Chakravarty, Debamitra, Dhavale, Dilip D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044920/
https://www.ncbi.nlm.nih.gov/pubmed/30023541
http://dx.doi.org/10.1021/acsomega.7b01299

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044920/
https://www.ncbi.nlm.nih.gov/pubmed/30023541
http://dx.doi.org/10.1021/acsomega.7b01299

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