Improved Solubility and Bioactivity of Camptothecin Family Antitumor Drugs with Supramolecular Encapsulation by Water-Soluble Pillar[6]arene

[Image: see text] Water-soluble pillar[6]arene (WP6) was used to solubilize camptothecin family antitumor drugs. In the presence of WP6, the solubility of camptothecin (CPT) and 10-hydroxycamptothecin (HCPT) was enhanced by 380 and 40 times, respectively. The solubility enhancement is proved to be t...

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Detalles Bibliográficos
Autores principales: Liu, Yamin, Chen, Xi, Ding, Jiaming, Yu, Lin, Ma, Da, Ding, Jiandong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044948/
https://www.ncbi.nlm.nih.gov/pubmed/30023745
http://dx.doi.org/10.1021/acsomega.7b01032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044948/
https://www.ncbi.nlm.nih.gov/pubmed/30023745
http://dx.doi.org/10.1021/acsomega.7b01032

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