Cargando…
Molecular Insights into the Membrane Affinities of Model Hydrophobes
[Image: see text] Membrane-active antibiotics are of great interest in fighting bacterial resistance. α-Mangostin is a membrane-active molecule, but there are no details of its mechanism of action at the atomistic level. We have employed free-energy simulations and microsecond-long conventional mole...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2018
|
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044992/ https://www.ncbi.nlm.nih.gov/pubmed/30023836 http://dx.doi.org/10.1021/acsomega.7b01759 |