Novel Low-Toxic Derivative of Celastrol Maintains Protective Effect against Acute Renal Injury

[Image: see text] This study aimed to novelly design and synthesize an amide derivative as a potential substitute of celastrol (CLT). We constituted the compound celastrol–glucosamine (CLG) by conjugating 1-(2-aminoethoxy)-2-glucosamine to celastrol (CLT) and confirmed its chemical structure by (1)H...

Descripción completa

Detalles Bibliográficos
Autores principales: Hu, Xun, Jia, Mengdi, Fu, Yu, Zhang, Pei, Zhang, Zhirong, Lin, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045326/
https://www.ncbi.nlm.nih.gov/pubmed/30023844
http://dx.doi.org/10.1021/acsomega.7b01890

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045326/
https://www.ncbi.nlm.nih.gov/pubmed/30023844
http://dx.doi.org/10.1021/acsomega.7b01890

Ejemplares similares