Cargando…
Novel Low-Toxic Derivative of Celastrol Maintains Protective Effect against Acute Renal Injury
[Image: see text] This study aimed to novelly design and synthesize an amide derivative as a potential substitute of celastrol (CLT). We constituted the compound celastrol–glucosamine (CLG) by conjugating 1-(2-aminoethoxy)-2-glucosamine to celastrol (CLT) and confirmed its chemical structure by (1)H...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2018
|
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045326/ https://www.ncbi.nlm.nih.gov/pubmed/30023844 http://dx.doi.org/10.1021/acsomega.7b01890 |