Cargando…

Downregulation of exosomal miR-204-5p and miR-632 as a biomarker for FTD: a GENFI study

OBJECTIVE: To determine whether exosomal microRNAs (miRNAs) in cerebrospinal fluid (CSF) of patients with frontotemporal dementia (FTD) can serve as diagnostic biomarkers, we assessed miRNA expression in the Genetic Frontotemporal Dementia Initiative (GENFI) cohort and in sporadic FTD. METHODS: GENF...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schneider, Raphael, McKeever, Paul, Kim, TaeHyung, Graff, Caroline, van Swieten, John Cornelis, Karydas, Anna, Boxer, Adam, Rosen, Howie, Miller, Bruce L, Laforce Jr, Robert, Galimberti, Daniela, Masellis, Mario, Borroni, Barbara, Zhang, Zhaolei, Zinman, Lorne, Rohrer, Jonathan Daniel, Tartaglia, Maria Carmela, Robertson, Janice
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2018
Materias:	Cognitive Neurology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045452/ https://www.ncbi.nlm.nih.gov/pubmed/29434051 http://dx.doi.org/10.1136/jnnp-2017-317492

Ejemplares similares

Altered plasma protein profiles in genetic FTD – a GENFI study
por: Ullgren, Abbe, et al.
Publicado: (2023)

Differential early subcortical involvement in genetic FTD within the GENFI cohort
por: Bocchetta, Martina, et al.
Publicado: (2021)

miR-632 promotes gastric cancer progression by accelerating angiogenesis in a TFF1-dependent manner
por: Shi, Ying, et al.
Publicado: (2019)

White matter hyperintensities are seen only in GRN mutation carriers in the GENFI cohort
por: Sudre, Carole H., et al.
Publicado: (2017)

Diagnostic and prognostic potential of serum miR-7, miR-16, miR-25, miR-93, miR-182, miR-376a and miR-429 in ovarian cancer patients
por: Meng, Xiaodan, et al.
Publicado: (2015)

Patterns of gray matter atrophy in genetic frontotemporal dementia: results from the GENFI study
por: Cash, David M., et al.
Publicado: (2018)

miR-1, miR-10b, miR-155, and miR-191 are novel regulators of BDNF
por: Varendi, Kärt, et al.
Publicado: (2014)

Interactions of miR-323/miR-326/miR-329 and miR-130a/miR-155/miR-210 as prognostic indicators for clinical outcome of glioblastoma patients
por: Qiu, Shuwei, et al.
Publicado: (2013)

Clinical relevance of microRNA miR-21, miR-31, miR-92a, miR-101, miR-106a and miR-145 in colorectal cancer
por: Schee, Kristina, et al.
Publicado: (2012)

Distinct Neuroanatomical Correlates of Neuropsychiatric Symptoms in the Three Main Forms of Genetic Frontotemporal Dementia in the GENFI Cohort
por: Sellami, Leila, et al.
Publicado: (2018)

miR-632 Induces DNAJB6 Inhibition Stimulating Endothelial-to-Mesenchymal Transition and Fibrosis in Marfan Syndrome Aortopathy
por: Terriaca, Sonia, et al.
Publicado: (2023)

Up-Regulation of miR-21, miR-25, miR-93, and miR-106b in Gastric Cancer
por: Larki, Pegah, et al.
Publicado: (2018)

Serum levels of miR-29, miR-122, miR-155 and miR-192 are elevated in patients with cholangiocarcinoma
por: Loosen, Sven H., et al.
Publicado: (2019)

Microvesicle-associated and circulating microRNAs in diabetic dyslipidemia: miR-218, miR-132, miR-143, and miR-21, miR-122, miR-155 have biomarker potential
por: Nemecz, Miruna, et al.
Publicado: (2023)

Elevated Serum miR-7, miR-9, miR-122, and miR-141 Are Noninvasive Biomarkers of Acute Pancreatitis
por: Lu, Pan, et al.
Publicado: (2017)

miR-632 Promotes Laryngeal Carcinoma Cell Proliferation, Migration, and Invasion Through Negative Regulation of GSK3β
por: Zhou, Zhong-xin, et al.
Publicado: (2020)

MiR-CLIP reveals iso-miR selective regulation in the miR-124 targetome
por: Wang, Yuluan, et al.
Publicado: (2020)

Spatiotemporal analysis for detection of pre-symptomatic shape changes in neurodegenerative diseases: Initial application to the GENFI cohort
por: Cury, Claire, et al.
Publicado: (2019)

miR-17, miR-19b, miR-20a, and miR-106a are down-regulated in human aging
por: Hackl, Matthias, et al.
Publicado: (2010)

MicroRNAs miR-19, miR-340, miR-374 and miR-542 regulate MID1 protein expression
por: Unterbruner, Kristoffer, et al.
Publicado: (2018)

The clinical significance of circulating miR-21, miR-142, miR-143, and miR-146a in patients with prostate cancer
por: Bolayırlı, Ibrahim Murat, et al.
Publicado: (2022)

miR-496, miR-1185, miR-654, miR-3183 and miR-495 are downregulated in colorectal cancer cells and have putative roles in the mTOR pathway
por: Alqurashi, Naif, et al.
Publicado: (2019)

Cognitive composites for genetic frontotemporal dementia: GENFI-Cog
por: Poos, Jackie M., et al.
Publicado: (2022)

Post-transcriptional Regulation of PCSK9 by miR-191, miR-222, and miR-224
por: Naeli, Parisa, et al.
Publicado: (2017)

FAIM Is Regulated by MiR-206, MiR-1-3p and MiR-133b
por: Coccia, Elena, et al.
Publicado: (2020)

Expression of miR-127, miR-154, and miR-183 in Medullary Thyroid Carcinoma Tumors
por: RAHMANI SAMANI, Mahsa, et al.
Publicado: (2021)

Expression of miR-210, miR-137, and miR-153 in Patients with Acute Cerebral Infarction
por: Tian, Hongtao, et al.
Publicado: (2021)

Circulating microRNAs, miR-939, miR-595, miR-519d and miR-494, Identify Cirrhotic Patients with HCC
por: Fornari, Francesca, et al.
Publicado: (2015)

Differential expression of miR-1297, miR-3191-5p, miR-4435, and miR-4465 in malignant and benign breast tumors
por: Mosapour, Abbas, et al.
Publicado: (2020)

Genetic Variants miR-126, miR-146a, miR-196a2, and miR-499 in Polycystic Ovary Syndrome
por: Li, R., et al.
Publicado: (2022)

Lack of association between miR-27a, miR-146a, miR-196a-2, miR-492 and miR-608 gene polymorphisms and colorectal cancer
por: Kupcinskas, Juozas, et al.
Publicado: (2014)

miR-21, miR-93, miR-191, miR-let-7b, and miR-499 Expression Level in Plasma and Cerebrospinal Fluid in Patients with Prolonged Disorders of Consciousness
por: Petrova, Tatiana A., et al.
Publicado: (2022)

NF‐κB inhibition reverses acidic bile‐induced miR‐21, miR‐155, miR‐192, miR‐34a, miR‐375 and miR‐451a deregulations in human hypopharyngeal cells
por: Doukas, Sotirios G., et al.
Publicado: (2018)

Exosomal miRNA Expression Profiling and the Roles of Exosomal miR-4741, miR-32, miR-3149, and miR-6727 on Gastric Cancer Progression
por: Tang, Guojun, et al.
Publicado: (2022)

Social cognition impairment in genetic frontotemporal dementia within the GENFI cohort
por: Russell, Lucy L., et al.
Publicado: (2020)

Expression of miR-1, miR-133a, miR-133b and miR-206 increases during development of human skeletal muscle
por: Koutsoulidou, Andrie, et al.
Publicado: (2011)

Methylation of miR-34a, miR-34b/c, miR-124-1 and miR-203 in Ph-negative myeloproliferative neoplasms
por: Chim, Chor Sang, et al.
Publicado: (2011)

Circulating miR-17, miR-20a, miR-29c, and miR-223 Combined as Non-Invasive Biomarkers in Nasopharyngeal Carcinoma
por: Zeng, Xi, et al.
Publicado: (2012)

Diagnostic and prognostic potential of miR-21, miR-29c, miR-148 and miR-203 in adenocarcinoma and squamous cell carcinoma of esophagus
por: Hezova, Renata, et al.
Publicado: (2015)

MiR-21, miR-34a, miR-198 and miR-217 as diagnostic and prognostic biomarkers for chronic pancreatitis and pancreatic ductal adenocarcinoma
por: Vychytilova-Faltejskova, Petra, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_bp8oucaj17v69s5ru2kkjq3bko