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Ultrafine Highly Magnetic Fluorescent γ-Fe(2)O(3)/NCD Nanocomposites for Neuronal Manipulations
[Image: see text] In this work, we describe a low-cost, two-step synthesis of composites of nitrogen-doped carbon quantum dots (NCDs) with γ-Fe(2)O(3) (NCDs/γ-Fe(2)O(3)), which is based on a hydrothermal cum co-precipitation method. The product is a fine powder of particles having an average diamete...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045473/ https://www.ncbi.nlm.nih.gov/pubmed/30023817 http://dx.doi.org/10.1021/acsomega.7b01666 |
Sumario: | [Image: see text] In this work, we describe a low-cost, two-step synthesis of composites of nitrogen-doped carbon quantum dots (NCDs) with γ-Fe(2)O(3) (NCDs/γ-Fe(2)O(3)), which is based on a hydrothermal cum co-precipitation method. The product is a fine powder of particles having an average diameter of 9 ± 3 nm. The physical and chemical properties of NCDs/γ-Fe(2)O(3) were studied, as well as the superconducting quantum interference device and Mossbauer analysis of the magnetic properties of these nanocomposites. The interaction of NCDs/γ-Fe(2)O(3) nanocomposites with neuron-like cells was examined, showing efficient uptake and low toxicity. Our research demonstrates the use of the nanocomposites for imaging and for controlling the cellular motility. The NCDs/γ-Fe(2)O(3) nanocomposites are promising because of their biocompatibility, photostability, and potential selective affinity, paving the way for multifunctional biomedical applications. |
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