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Therapeutic Radiopharmaceuticals Targeting Integrin αvβ6

[Image: see text] The epithelial integrin αvβ6 is expressed by many malignant carcinoma cell types, including pancreatic cancer, and thus represents a promising target for radionuclide therapy. The peptide cyclo(FRGDLAFp(NMe)K) was decorated with different chelators (DOTPI, DOTAGA, and DOTA). The Lu...

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Detalles Bibliográficos
Autores principales: Färber, Stefanie Felicitas, Wurzer, Alexander, Reichart, Florian, Beck, Roswitha, Kessler, Horst, Wester, Hans-Jürgen, Notni, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045477/
https://www.ncbi.nlm.nih.gov/pubmed/30023833
http://dx.doi.org/10.1021/acsomega.8b00035