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White-Light-Activated Antibacterial Surfaces Generated by Synergy between Zinc Oxide Nanoparticles and Crystal Violet
[Image: see text] The prevalence of hospital-acquired infections (HAIs) caused by multidrug-resistant bacteria is a growing public health concern worldwide. Herein, a facile, easily scalable technique is reported to fabricate white-light-activated bactericidal surfaces by incorporating zinc oxide (Z...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045480/ https://www.ncbi.nlm.nih.gov/pubmed/30023864 http://dx.doi.org/10.1021/acsomega.7b01473 |
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author | Ozkan, Ekrem Allan, Elaine Parkin, Ivan P. |
author_facet | Ozkan, Ekrem Allan, Elaine Parkin, Ivan P. |
author_sort | Ozkan, Ekrem |
collection | PubMed |
description | [Image: see text] The prevalence of hospital-acquired infections (HAIs) caused by multidrug-resistant bacteria is a growing public health concern worldwide. Herein, a facile, easily scalable technique is reported to fabricate white-light-activated bactericidal surfaces by incorporating zinc oxide (ZnO) nanoparticles and crystal violet (CV) dye into poly(dimethylsiloxane). The effect of ZnO concentration on photobactericidal activity of CV is investigated, and we show that there is synergy between ZnO and CV. These materials showed highly significant antibacterial activity when tested against Staphylococcus aureus and Escherichia coli under white light conditions. These surfaces have potential to be used in healthcare environments to decrease the impact of HAIs. |
format | Online Article Text |
id | pubmed-6045480 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | American Chemical Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-60454802018-07-16 White-Light-Activated Antibacterial Surfaces Generated by Synergy between Zinc Oxide Nanoparticles and Crystal Violet Ozkan, Ekrem Allan, Elaine Parkin, Ivan P. ACS Omega [Image: see text] The prevalence of hospital-acquired infections (HAIs) caused by multidrug-resistant bacteria is a growing public health concern worldwide. Herein, a facile, easily scalable technique is reported to fabricate white-light-activated bactericidal surfaces by incorporating zinc oxide (ZnO) nanoparticles and crystal violet (CV) dye into poly(dimethylsiloxane). The effect of ZnO concentration on photobactericidal activity of CV is investigated, and we show that there is synergy between ZnO and CV. These materials showed highly significant antibacterial activity when tested against Staphylococcus aureus and Escherichia coli under white light conditions. These surfaces have potential to be used in healthcare environments to decrease the impact of HAIs. American Chemical Society 2018-03-15 /pmc/articles/PMC6045480/ /pubmed/30023864 http://dx.doi.org/10.1021/acsomega.7b01473 Text en Copyright © 2018 American Chemical Society This is an open access article published under a Creative Commons Attribution (CC-BY) License (http://pubs.acs.org/page/policy/authorchoice_ccby_termsofuse.html) , which permits unrestricted use, distribution and reproduction in any medium, provided the author and source are cited. |
spellingShingle | Ozkan, Ekrem Allan, Elaine Parkin, Ivan P. White-Light-Activated Antibacterial Surfaces Generated by Synergy between Zinc Oxide Nanoparticles and Crystal Violet |
title | White-Light-Activated Antibacterial Surfaces Generated
by Synergy between Zinc Oxide Nanoparticles and Crystal Violet |
title_full | White-Light-Activated Antibacterial Surfaces Generated
by Synergy between Zinc Oxide Nanoparticles and Crystal Violet |
title_fullStr | White-Light-Activated Antibacterial Surfaces Generated
by Synergy between Zinc Oxide Nanoparticles and Crystal Violet |
title_full_unstemmed | White-Light-Activated Antibacterial Surfaces Generated
by Synergy between Zinc Oxide Nanoparticles and Crystal Violet |
title_short | White-Light-Activated Antibacterial Surfaces Generated
by Synergy between Zinc Oxide Nanoparticles and Crystal Violet |
title_sort | white-light-activated antibacterial surfaces generated
by synergy between zinc oxide nanoparticles and crystal violet |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045480/ https://www.ncbi.nlm.nih.gov/pubmed/30023864 http://dx.doi.org/10.1021/acsomega.7b01473 |
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