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UCS protein function is partially restored in the Saccharomyces cerevisiae she4 mutant with expression of the human UNC45-GC, but not UNC45-SM
A dedicated UNC45, Cro1, She4 (UCS) domain-containing protein assists in the Hsp90-mediated folding of the myosin head. Only weak sequence conservation exists between the single UCS protein of simple eukaryotes (She4 in budding yeast) and the two UCS proteins of higher organisms (the general cell an...
Autores principales: | Escalante, Susana Gómez, Brightmore, Joseph A., Piper, Peter W., Millson, Stefan H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045556/ https://www.ncbi.nlm.nih.gov/pubmed/29288355 http://dx.doi.org/10.1007/s12192-017-0870-1 |
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