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Highly efficient RNA-guided base editing in rabbit

Cytidine base editors (CBEs) and adenine base editors (ABEs), composed of a cytidine deaminase or an evolved adenine deaminase fused to Cas9 nickase, enable the conversion of C·G to T·A or A·T to G·C base pair in organisms, respectively. Here, we show that BE3 and ABE7.10 systems can achieve a targe...

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Detalles Bibliográficos
Autores principales:	Liu, Zhiquan, Chen, Mao, Chen, Siyu, Deng, Jichao, Song, Yuning, Lai, Liangxue, Li, Zhanjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045575/ https://www.ncbi.nlm.nih.gov/pubmed/30006570 http://dx.doi.org/10.1038/s41467-018-05232-2

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