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Transcriptional and post-transcriptional regulation of PenA β-lactamase in acquired Burkholderia pseudomallei β-lactam resistance
Therapy of Burkholderia pseudomallei acute infections is largely limited to a few β-lactam antibiotics such as ceftazidime or meropenem. Although relatively rare, resistance emergence during therapy leads to treatment failures with high mortality rates. In the absence of acquired external resistance...
Autores principales: | Chirakul, Sunisa, Norris, Michael H., Pagdepanichkit, Sirawit, Somprasong, Nawarat, Randall, Linnell B., Shirley, James F., Borlee, Bradley R., Lomovskaya, Olga, Tuanyok, Apichai, Schweizer, Herbert P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045580/ https://www.ncbi.nlm.nih.gov/pubmed/30006637 http://dx.doi.org/10.1038/s41598-018-28843-7 |
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