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A broad-spectrum antibiotic, DCAP, reduces uropathogenic Escherichia coli infection and enhances vorinostat anticancer activity by modulating autophagy

The cellular recycling pathway of autophagy plays a fundamental role in adaptive responses to nutrient deprivation and other forms of stress under physiological and pathological conditions. However, autophagy can also be a double-edge sword during certain bacterial infections (such as urinary tract...

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Detalles Bibliográficos
Autores principales: Allavena, Giulia, Debellis, Doriana, Marotta, Roberto, Joshi, Chetanchandra S., Mysorekar, Indira U., Grimaldi, Benedetto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045594/
https://www.ncbi.nlm.nih.gov/pubmed/30006504
http://dx.doi.org/10.1038/s41419-018-0786-4