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Nicotine aversion is mediated by GABAergic interpeduncular nucleus inputs to laterodorsal tegmentum

Nicotine use can lead to dependence through complex processes that are regulated by both its rewarding and aversive effects. Recent studies show that aversive nicotine doses activate excitatory inputs to the interpeduncular nucleus (IPN) from the medial habenula (MHb), but the downstream targets of...

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Detalles Bibliográficos
Autores principales: Wolfman, Shannon L., Gill, Daniel F., Bogdanic, Fili, Long, Katie, Al-Hasani, Ream, McCall, Jordan G., Bruchas, Michael R., McGehee, Daniel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045623/
https://www.ncbi.nlm.nih.gov/pubmed/30006624
http://dx.doi.org/10.1038/s41467-018-04654-2

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