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Nicotine aversion is mediated by GABAergic interpeduncular nucleus inputs to laterodorsal tegmentum
Nicotine use can lead to dependence through complex processes that are regulated by both its rewarding and aversive effects. Recent studies show that aversive nicotine doses activate excitatory inputs to the interpeduncular nucleus (IPN) from the medial habenula (MHb), but the downstream targets of...
Autores principales: | Wolfman, Shannon L., Gill, Daniel F., Bogdanic, Fili, Long, Katie, Al-Hasani, Ream, McCall, Jordan G., Bruchas, Michael R., McGehee, Daniel S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045623/ https://www.ncbi.nlm.nih.gov/pubmed/30006624 http://dx.doi.org/10.1038/s41467-018-04654-2 |
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