Cargando…

HIV-associated cardiovascular disease: importance of platelet activation and cardiac fibrosis in the setting of specific antiretroviral therapies

HIV infection is a risk factor for cardiovascular disease (CVD). This risk is accentuated by certain combination antiretroviral therapies (cARTs), independent of their effects on lipid metabolism and insulin sensitivity. We sought to define potential mechanisms for this association through systemati...

Descripción completa

Detalles Bibliográficos
Autores principales:	Laurence, Jeffrey, Elhadad, Sonia, Ahamed, Jasimuddin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2018
Materias:	Basic and Translational Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045710/ https://www.ncbi.nlm.nih.gov/pubmed/30018781 http://dx.doi.org/10.1136/openhrt-2018-000823

Ejemplares similares

HIV protease inhibitor-induced cardiac dysfunction and fibrosis is mediated by platelet-derived TGF-β1 and can be suppressed by exogenous carbon monoxide
por: Laurence, Jeffrey, et al.
Publicado: (2017)

Blocking CXCL9 Decreases HIV-1 Replication and Enhances the Activity of Prophylactic Antiretrovirals in Human Cervical Tissues
por: Macura, Sherrill L., et al.
Publicado: (2016)

Pan PPAR agonist IVA337 is effective in prevention and treatment of experimental skin fibrosis
por: Ruzehaji, Nadira, et al.
Publicado: (2016)

Long COVID endotheliopathy: hypothesized mechanisms and potential therapeutic approaches
por: Ahamed, Jasimuddin, et al.
Publicado: (2022)

Involvement of platelet-derived VWF in metastatic growth of melanoma in the brain
por: Robador, Jose R, et al.
Publicado: (2021)

Defibrotide mitigates endothelial cell injury induced by plasmas from patients with COVID-19 and related vasculopathies
por: Elhadad, Sonia, et al.
Publicado: (2023)

Research priorities in cardiovascular imaging
por: Yong, Guo Liang, et al.
Publicado: (2020)

Glioma stem cells activate platelets by plasma-independent thrombin production to promote glioblastoma tumorigenesis
por: Sloan, Anthony R, et al.
Publicado: (2022)

Identification of five important genes to predict glioblastoma subtypes
por: Tang, Yang, et al.
Publicado: (2021)

Prognostic implications of epidermal and platelet-derived growth factor receptor alterations in 2 cohorts of IDHwt glioblastoma
por: Alnahhas, Iyad, et al.
Publicado: (2021)

Intervention in COVID-19 linked hypercoaguable states characterized by circuit thrombosis utilizing a direct thrombin inhibitor
por: Seshadri, Madhav, et al.
Publicado: (2020)

Importance of length and external diameter in left ventricular geometry. Normal values from the HUNT Study
por: Støylen, Asbjørn, et al.
Publicado: (2016)

Elevated serum levels of cardiovascular biomarkers are associated with progression of renal cancer
por: Kamai, Takao, et al.
Publicado: (2018)

The Effect of Therapeutic HIV Vaccination With ALVAC-HIV With or Without Remune on the Size of the Viral Reservoir (A CTN 173 Substudy)
por: Angel, Jonathan B., et al.
Publicado: (2015)

Premortem Skin Biopsy Assessing Microthrombi, Interferon Type I Antiviral and Regulatory Proteins, and Complement Deposition Correlates with Coronavirus Disease 2019 Clinical Stage
por: Laurence, Jeffrey, et al.
Publicado: (2022)

Evaluation of Rapid Progressors in HIV Infection as an Extreme Phenotype
por: Olson, Ashley D., et al.
Publicado: (2014)

Parvovirus B19 activates in vitro normal human dermal fibroblasts: a possible implication in skin fibrosis and systemic sclerosis
por: Arvia, Rosaria, et al.
Publicado: (2020)

Novel gene variants associated with cardiovascular disease in systemic lupus erythematosus and rheumatoid arthritis
por: Leonard, Dag, et al.
Publicado: (2018)

Environmental and sex-specific molecular signatures of glioma causation
por: Claus, Elizabeth B, et al.
Publicado: (2021)

Single-cell transcriptomic analyses provide insights into the cellular origins and drivers of brain metastasis from lung adenocarcinoma
por: Wang, Zihao, et al.
Publicado: (2023)

GBMdeconvoluteR accurately infers proportions of neoplastic and immune cell populations from bulk glioblastoma transcriptomics data
por: Ajaib, Shoaib, et al.
Publicado: (2023)

Immunization of HIV-1-Infected Persons With Autologous Dendritic Cells Transfected With mRNA Encoding HIV-1 Gag and Nef: Results of a Randomized, Placebo-Controlled Clinical Trial
por: Gandhi, Rajesh T., et al.
Publicado: (2016)

Association Between HIV-1 Coreceptor Usage and Resistance to Broadly Neutralizing Antibodies
por: Pfeifer, Nico, et al.
Publicado: (2014)

Variants in Host Viral Replication Cycle Genes Are Associated With Heterosexual HIV-1 Acquisition in Africans
por: Bigham, Abigail W., et al.
Publicado: (2014)

Raised cardiovascular disease mortality after central nervous system tumor diagnosis: analysis of 171,926 patients from UK and USA
por: Jin, Kai, et al.
Publicado: (2021)

V1/V2 Neutralizing Epitope is Conserved in Divergent Non-M Groups of HIV-1
por: Morgand, Marion, et al.
Publicado: (2016)

Cardiovascular MR T2-STIR imaging does not discriminate between intramyocardial haemorrhage and microvascular obstruction during the subacute phase of a reperfused myocardial infarction
por: Hansen, Esben Søvsø Szocska, et al.
Publicado: (2016)

Brief Report: Effect of CMV and HIV Transcription on CD57 and PD-1 T-Cell Expression During Suppressive ART
por: Dan, Jennifer M., et al.
Publicado: (2016)

Viral Decay Dynamics and Mathematical Modeling of Treatment Response: Evidence of Lower in vivo Fitness of HIV-1 Subtype C
por: Shet, Anita, et al.
Publicado: (2016)

Influence of Hepatitis C Virus Sustained Virological Response on Immunosuppressive Tryptophan Catabolism in ART-Treated HIV/HCV Coinfected Patients
por: Jenabian, Mohammad-Ali, et al.
Publicado: (2016)

Brief Report: HIV-1 Infection Impairs CD16 and CD35 Mediated Opsonophagocytosis of Mycobacterium tuberculosis by Human Neutrophils
por: Bangani, Nonzwakazi, et al.
Publicado: (2016)

Expression of cell type incongruent alpha-cardiac actin 1 subunit in medulloblastoma reveals a novel mechanism for cancer cell survival and control of migration
por: Suresh, Rahul, et al.
Publicado: (2021)

Impacts of HIV-1 Subtype Diversity on Long-Term Clinical Outcomes in Antiretroviral Therapy in Guangxi, China
por: Jiang, He, et al.
Publicado: (2022)

Brief Report: HIV-1 Evolution in Breakthrough Infections in a Human Trial of Oral Pre-exposure Prophylaxis With Emtricitabine and Tenofovir Disoproxil Fumarate
por: Ruone, Susan, et al.
Publicado: (2016)

Elevated Abundance, Size, and MicroRNA Content of Plasma Extracellular Vesicles in Viremic HIV-1+ Patients: Correlations With Known Markers of Disease Progression
por: Hubert, Audrey, et al.
Publicado: (2015)

Identification of 3 Distinct HIV-1 Founding Strains Responsible for Expanding Epidemic Among Men Who Have Sex With Men in 9 Chinese Cities
por: Han, Xiaoxu, et al.
Publicado: (2013)

Virological and immunological correlates of HIV posttreatment control after temporal antiretroviral therapy during acute HIV infection
por: van Paassen, Pien M., et al.
Publicado: (2023)

HIV-1 Drug Resistance by Ultra-Deep Sequencing Following Short Course Zidovudine, Single-Dose Nevirapine, and Single-Dose Tenofovir with Emtricitabine for Prevention of Mother-to-Child Transmission
por: Samuel, Reshmi, et al.
Publicado: (2016)

Brief Report: A High Rate of β7(+) Gut-Homing Lymphocytes in HIV-Infected Immunological Nonresponders is Associated With Poor CD4 T-Cell Recovery During Suppressive HAART
por: Girard, Alexandre, et al.
Publicado: (2016)

2042 CYP2C19*2 and PON1 Q192R polymorphisms are associated with platelet reactivity to clopidogrel in Puerto Rican Hispanics with cardiovascular disease
por: Suarez, Dagmar F. H., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_d3828e3iejlb4ms1l64568ckes