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Plasma myeloperoxidase-conjugated DNA level predicts outcomes and organ dysfunction in patients with septic shock

BACKGROUND: Recent studies have suggested that excessive formation of neutrophil extracellular traps (NETs) plays a critical role in the pathogenesis of sepsis. Although elevation of the plasma level of cell-free DNA (cf-DNA) has been reported in sepsis patients, there has been little direct measure...

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Detalles Bibliográficos
Autores principales: Maruchi, Yuki, Tsuda, Masanobu, Mori, Hisatake, Takenaka, Nobuyoshi, Gocho, Takayoshi, Huq, Muhammad A., Takeyama, Naoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045839/
https://www.ncbi.nlm.nih.gov/pubmed/30005596
http://dx.doi.org/10.1186/s13054-018-2109-7