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Pulmonary vein anatomy variants as a biomarker of atrial fibrillation – CT angiography evaluation
BACKGROUND: It has been suggested that changes in pulmonary veins (PV) and left atrium (LA) anatomy may have an influence on initiating atrial fibrillation (AF) and the effectiveness of pulmonary vein isolation (PVI) in patients (pts) with atrial fibrillation. The aim of the study was to assess anat...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045862/ https://www.ncbi.nlm.nih.gov/pubmed/30005637 http://dx.doi.org/10.1186/s12872-018-0884-3 |
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author | Skowerski, M. Wozniak-Skowerska, I. Hoffmann, A. Nowak, S. Skowerski, T. Sosnowski, M. Wnuk-Wojnar, A. M. Mizia-Stec, K. |
author_facet | Skowerski, M. Wozniak-Skowerska, I. Hoffmann, A. Nowak, S. Skowerski, T. Sosnowski, M. Wnuk-Wojnar, A. M. Mizia-Stec, K. |
author_sort | Skowerski, M. |
collection | PubMed |
description | BACKGROUND: It has been suggested that changes in pulmonary veins (PV) and left atrium (LA) anatomy may have an influence on initiating atrial fibrillation (AF) and the effectiveness of pulmonary vein isolation (PVI) in patients (pts) with atrial fibrillation. The aim of the study was to assess anatomy abnormalities of the PV and LA in the patients with the history of AF and compare it with the control group(CG). METHODS: The multi-slice tomography (MSCT) scans were performed in 224 AF pts. before PVI (129 males, mean age 59 ± 9 yrs). The CG consisted of 40 pts. without AF (26 males, age 45 ± 9 yrs). LA and PV anatomy were evaluated. Diameters of PV ostia were measured in two directions: anterior-posterior (AP) and superior-inferior (SI) automatically using Vitrea 4.0. RESULTS: Pulmonary veins anatomy variants were observed more frequently in the atrial fibrillation group - 83 pts. (37%) vs 6 pts. (15%) in CG; 9% (21 pts) left common ostia (CO), 2% (5 pts) right CO, 19% (42 pts) additional right PV (APV), (1.8%) 4 pts. APV left, 8% right early branching (EB) and 3.5% left EB. The LA diameter differed significantly in AF vs CG group (41.2 ± 6 mm vs 35 ± 4.2 mm, p < 0.0001) respectively. CONCLUSIONS: The anomalies of pulmonary vein anatomy occurred more often in pts. with AF. They can be defined as an image biomarkers of atrial fibrillation. Right additional (middle) pulmonary vein was the most important anomaly detected in AF patients as well as enlargered diameters of the LA and PV ostia. |
format | Online Article Text |
id | pubmed-6045862 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-60458622018-07-16 Pulmonary vein anatomy variants as a biomarker of atrial fibrillation – CT angiography evaluation Skowerski, M. Wozniak-Skowerska, I. Hoffmann, A. Nowak, S. Skowerski, T. Sosnowski, M. Wnuk-Wojnar, A. M. Mizia-Stec, K. BMC Cardiovasc Disord Research Article BACKGROUND: It has been suggested that changes in pulmonary veins (PV) and left atrium (LA) anatomy may have an influence on initiating atrial fibrillation (AF) and the effectiveness of pulmonary vein isolation (PVI) in patients (pts) with atrial fibrillation. The aim of the study was to assess anatomy abnormalities of the PV and LA in the patients with the history of AF and compare it with the control group(CG). METHODS: The multi-slice tomography (MSCT) scans were performed in 224 AF pts. before PVI (129 males, mean age 59 ± 9 yrs). The CG consisted of 40 pts. without AF (26 males, age 45 ± 9 yrs). LA and PV anatomy were evaluated. Diameters of PV ostia were measured in two directions: anterior-posterior (AP) and superior-inferior (SI) automatically using Vitrea 4.0. RESULTS: Pulmonary veins anatomy variants were observed more frequently in the atrial fibrillation group - 83 pts. (37%) vs 6 pts. (15%) in CG; 9% (21 pts) left common ostia (CO), 2% (5 pts) right CO, 19% (42 pts) additional right PV (APV), (1.8%) 4 pts. APV left, 8% right early branching (EB) and 3.5% left EB. The LA diameter differed significantly in AF vs CG group (41.2 ± 6 mm vs 35 ± 4.2 mm, p < 0.0001) respectively. CONCLUSIONS: The anomalies of pulmonary vein anatomy occurred more often in pts. with AF. They can be defined as an image biomarkers of atrial fibrillation. Right additional (middle) pulmonary vein was the most important anomaly detected in AF patients as well as enlargered diameters of the LA and PV ostia. BioMed Central 2018-07-13 /pmc/articles/PMC6045862/ /pubmed/30005637 http://dx.doi.org/10.1186/s12872-018-0884-3 Text en © The Author(s). 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Article Skowerski, M. Wozniak-Skowerska, I. Hoffmann, A. Nowak, S. Skowerski, T. Sosnowski, M. Wnuk-Wojnar, A. M. Mizia-Stec, K. Pulmonary vein anatomy variants as a biomarker of atrial fibrillation – CT angiography evaluation |
title | Pulmonary vein anatomy variants as a biomarker of atrial fibrillation – CT angiography evaluation |
title_full | Pulmonary vein anatomy variants as a biomarker of atrial fibrillation – CT angiography evaluation |
title_fullStr | Pulmonary vein anatomy variants as a biomarker of atrial fibrillation – CT angiography evaluation |
title_full_unstemmed | Pulmonary vein anatomy variants as a biomarker of atrial fibrillation – CT angiography evaluation |
title_short | Pulmonary vein anatomy variants as a biomarker of atrial fibrillation – CT angiography evaluation |
title_sort | pulmonary vein anatomy variants as a biomarker of atrial fibrillation – ct angiography evaluation |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045862/ https://www.ncbi.nlm.nih.gov/pubmed/30005637 http://dx.doi.org/10.1186/s12872-018-0884-3 |
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