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Liprin-α1 modulates cancer cell signaling by transmembrane protein CD82 in adhesive membrane domains linked to cytoskeleton

BACKGROUND: PPFIA1 is located at the 11q13 region commonly amplified in cancer. The protein liprin-α1 encoded by PPF1A1 contributes to the adhesive and invasive structures of cytoskeletal elements and is located at the invadosomes in cancer cells. However, the precise mechanism of liprin-α1 function...

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Detalles Bibliográficos
Autores principales:	Pehkonen, Henna, Lento, Mira, von Nandelstadh, Pernilla, Filippou, Artemis, Grénman, Reidar, Lehti, Kaisa, Monni, Outi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045882/ https://www.ncbi.nlm.nih.gov/pubmed/30005669 http://dx.doi.org/10.1186/s12964-018-0253-y

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