Cargando…

Multiple Organ Dysfunction Syndrome (MODS) induced by Candida krusei in an Aldabra giant tortoise (Aldabrachelys gigantea) and confirmed by electron microscopy analysis

A young female Aldabra giant tortoise (Adabrachelys gigantea) was presented with anorexia, ataxia, severe constipation and bloating. Analysis revealed liver disease and collected biopsy diagnosed Candida krusei infection. Despite Itraconazole treatment, the tortoise got worse and died. Full necropsy...

Descripción completa

Detalles Bibliográficos
Autores principales: Iannaccone, Maddalena, Basso, Petra Rita, Congiu, Terenzio, Cavicchio, Paolo, Ulivi, Valentina, Campolo, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045929/
https://www.ncbi.nlm.nih.gov/pubmed/30023165
http://dx.doi.org/10.1016/j.mmcr.2018.04.002
_version_ 1783339754612326400
author Iannaccone, Maddalena
Basso, Petra Rita
Congiu, Terenzio
Cavicchio, Paolo
Ulivi, Valentina
Campolo, Marco
author_facet Iannaccone, Maddalena
Basso, Petra Rita
Congiu, Terenzio
Cavicchio, Paolo
Ulivi, Valentina
Campolo, Marco
author_sort Iannaccone, Maddalena
collection PubMed
description A young female Aldabra giant tortoise (Adabrachelys gigantea) was presented with anorexia, ataxia, severe constipation and bloating. Analysis revealed liver disease and collected biopsy diagnosed Candida krusei infection. Despite Itraconazole treatment, the tortoise got worse and died. Full necropsy was performed; microbiology showed Candida krusei presence in liver, but histopathology didn’t confirm fungal presence with special stains, so scanning electron microscopy was essential to prove a detailed diagnosis of extensive mycosis.
format Online
Article
Text
id pubmed-6045929
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-60459292018-07-18 Multiple Organ Dysfunction Syndrome (MODS) induced by Candida krusei in an Aldabra giant tortoise (Aldabrachelys gigantea) and confirmed by electron microscopy analysis Iannaccone, Maddalena Basso, Petra Rita Congiu, Terenzio Cavicchio, Paolo Ulivi, Valentina Campolo, Marco Med Mycol Case Rep Case Report A young female Aldabra giant tortoise (Adabrachelys gigantea) was presented with anorexia, ataxia, severe constipation and bloating. Analysis revealed liver disease and collected biopsy diagnosed Candida krusei infection. Despite Itraconazole treatment, the tortoise got worse and died. Full necropsy was performed; microbiology showed Candida krusei presence in liver, but histopathology didn’t confirm fungal presence with special stains, so scanning electron microscopy was essential to prove a detailed diagnosis of extensive mycosis. Elsevier 2018-04-22 /pmc/articles/PMC6045929/ /pubmed/30023165 http://dx.doi.org/10.1016/j.mmcr.2018.04.002 Text en © 2018 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Iannaccone, Maddalena
Basso, Petra Rita
Congiu, Terenzio
Cavicchio, Paolo
Ulivi, Valentina
Campolo, Marco
Multiple Organ Dysfunction Syndrome (MODS) induced by Candida krusei in an Aldabra giant tortoise (Aldabrachelys gigantea) and confirmed by electron microscopy analysis
title Multiple Organ Dysfunction Syndrome (MODS) induced by Candida krusei in an Aldabra giant tortoise (Aldabrachelys gigantea) and confirmed by electron microscopy analysis
title_full Multiple Organ Dysfunction Syndrome (MODS) induced by Candida krusei in an Aldabra giant tortoise (Aldabrachelys gigantea) and confirmed by electron microscopy analysis
title_fullStr Multiple Organ Dysfunction Syndrome (MODS) induced by Candida krusei in an Aldabra giant tortoise (Aldabrachelys gigantea) and confirmed by electron microscopy analysis
title_full_unstemmed Multiple Organ Dysfunction Syndrome (MODS) induced by Candida krusei in an Aldabra giant tortoise (Aldabrachelys gigantea) and confirmed by electron microscopy analysis
title_short Multiple Organ Dysfunction Syndrome (MODS) induced by Candida krusei in an Aldabra giant tortoise (Aldabrachelys gigantea) and confirmed by electron microscopy analysis
title_sort multiple organ dysfunction syndrome (mods) induced by candida krusei in an aldabra giant tortoise (aldabrachelys gigantea) and confirmed by electron microscopy analysis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045929/
https://www.ncbi.nlm.nih.gov/pubmed/30023165
http://dx.doi.org/10.1016/j.mmcr.2018.04.002
work_keys_str_mv AT iannacconemaddalena multipleorgandysfunctionsyndromemodsinducedbycandidakruseiinanaldabragianttortoisealdabrachelysgiganteaandconfirmedbyelectronmicroscopyanalysis
AT bassopetrarita multipleorgandysfunctionsyndromemodsinducedbycandidakruseiinanaldabragianttortoisealdabrachelysgiganteaandconfirmedbyelectronmicroscopyanalysis
AT congiuterenzio multipleorgandysfunctionsyndromemodsinducedbycandidakruseiinanaldabragianttortoisealdabrachelysgiganteaandconfirmedbyelectronmicroscopyanalysis
AT cavicchiopaolo multipleorgandysfunctionsyndromemodsinducedbycandidakruseiinanaldabragianttortoisealdabrachelysgiganteaandconfirmedbyelectronmicroscopyanalysis
AT ulivivalentina multipleorgandysfunctionsyndromemodsinducedbycandidakruseiinanaldabragianttortoisealdabrachelysgiganteaandconfirmedbyelectronmicroscopyanalysis
AT campolomarco multipleorgandysfunctionsyndromemodsinducedbycandidakruseiinanaldabragianttortoisealdabrachelysgiganteaandconfirmedbyelectronmicroscopyanalysis