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Increased DNA Copy Number Variation Mosaicism in Elderly Human Brain

Aging is a complex process strongly determined by genetics. Previous reports have shown that the genome of neuronal cells displays somatic genomic mosaicism including DNA copy number variations (CNVs). CNVs represent a significant source of genetic variation in the human genome and have been implica...

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Detalles Bibliográficos
Autores principales:	Villela, Darine, Suemoto, Claudia K., Leite, Renata, Pasqualucci, Carlos Augusto, Grinberg, Lea T., Pearson, Peter, Rosenberg, Carla
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046114/ https://www.ncbi.nlm.nih.gov/pubmed/30050570 http://dx.doi.org/10.1155/2018/2406170

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