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CircSNCA downregulation by pramipexole treatment mediates cell apoptosis and autophagy in Parkinson’s disease by targeting miR-7

We aimed to explore the mechanism of pramipexole (PPX) actions in the treatment of Parkinson’s disease (PD). Genes related to PD and PPX were screened through bioinformatics retrieval. The PD model was constructed by applying 1-methyl-4-phenylpyridinium (MMP+). The RNA expression levels of circSNCA,...

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Detalles Bibliográficos
Autores principales: Sang, Qiuling, Liu, Xiaoyang, Wang, Libo, Qi, Ling, Sun, Wenping, Wang, Weiyao, Sun, Yajuan, Zhang, Haina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046232/
https://www.ncbi.nlm.nih.gov/pubmed/29953413
http://dx.doi.org/10.18632/aging.101466