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Single-Cell Analyses of Human Eosinophils at High Resolution to Understand Compartmentalization and Vesicular Trafficking of Interferon-Gamma

Human eosinophils release numerous cytokines that are pre-synthesized and stored within their cytoplasmic-specific (secretory) granules. For example, high levels of interferon-gamma (IFN-γ) are constitutively expressed in these cells, but the intracellular compartments involved in the transport and...

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Detalles Bibliográficos
Autores principales: Carmo, Lívia A. S., Bonjour, Kennedy, Spencer, Lisa A., Weller, Peter F., Melo, Rossana C. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046373/
https://www.ncbi.nlm.nih.gov/pubmed/30038615
http://dx.doi.org/10.3389/fimmu.2018.01542