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The p38 MAPK Inhibitor SB203580 Abrogates Tumor Necrosis Factor-Induced Proliferative Expansion of Mouse CD4(+)Foxp3(+) Regulatory T Cells

There is now compelling evidence that tumor necrosis factor (TNF) preferentially activates and expands CD4(+)Foxp3(+) regulatory T cells (Tregs) through TNF receptor type II (TNFR2). However, it remains unclear which signaling transduction pathway(s) of TNFR2 is required for the stimulation of Tregs...

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Detalles Bibliográficos
Autores principales:	He, Tianzhen, Liu, Shuoyang, Chen, Shaokui, Ye, Jingyi, Wu, Xueqiang, Bian, Zhaoxiang, Chen, Xin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046375/ https://www.ncbi.nlm.nih.gov/pubmed/30038619 http://dx.doi.org/10.3389/fimmu.2018.01556

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