In Situ Humoral Immunity to Vimentin in HLA-DRB1*03(+) Patients With Pulmonary Sarcoidosis

Vimentin has been implicated in pulmonary sarcoidosis as a T-cell autoantigen, particularly in the context of HLA-DRB1*03, the Vα2.3/Vβ22 T-cell receptor (TCR), and Löfgren’s syndrome. As vimentin is a known antigenic target in B-cell-mediated autoimmunity, we investigated in situ humoral anti-vimen...

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Detalles Bibliográficos
Autores principales: Kinloch, Andrew J., Kaiser, Ylva, Wolfgeher, Don, Ai, Junting, Eklund, Anders, Clark, Marcus R., Grunewald, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046378/
https://www.ncbi.nlm.nih.gov/pubmed/30038611
http://dx.doi.org/10.3389/fimmu.2018.01516

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046378/
https://www.ncbi.nlm.nih.gov/pubmed/30038611
http://dx.doi.org/10.3389/fimmu.2018.01516

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