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Gain of Function for the SCN1A/hNa(v)1.1-L1670W Mutation Responsible for Familial Hemiplegic Migraine
The SCN1A gene encodes for the voltage-dependent Na(v)1.1 Na(+) channel, an isoform mainly expressed in GABAergic neurons that is the target of hundreds of epileptogenic mutations. More recently, it has been shown that the SCN1A gene is also the target of mutations responsible for familial hemiplegi...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046441/ https://www.ncbi.nlm.nih.gov/pubmed/30038559 http://dx.doi.org/10.3389/fnmol.2018.00232 |