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Gossypol Inhibits Non-small Cell Lung Cancer Cells Proliferation by Targeting EGFR(L858R/T790M)
Background: Overexpression of epidermal growth factor receptor (EGFR) has been reported to be implicated in the pathogenesis of non-small cell lung cancer (NSCLC). Several EGFR inhibitors have been used in clinical treatment of NSCLC, but the emergence of EGFR(L858R/T790M) resistant mutation has red...
Autores principales: | Wang, Yuwei, Lai, Huanling, Fan, Xingxing, Luo, Lianxiang, Duan, Fugang, Jiang, Zebo, Wang, Qianqian, Leung, Elaine Lai Han, Liu, Liang, Yao, Xiaojun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046546/ https://www.ncbi.nlm.nih.gov/pubmed/30038571 http://dx.doi.org/10.3389/fphar.2018.00728 |
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