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Performing and interpreting individual pharmacokinetic profiles in patients with Hemophilia A or B: Rationale and general considerations

OBJECTIVES: In a separate document, we have provided specific guidance on performing individual pharmacokinetic (PK) studies using limited samples in persons with hemophilia with the goal to optimize prophylaxis with clotting factor concentrates. This paper, intended for clinicians, aims to describe...

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Detalles Bibliográficos
Autores principales:	Iorio, Alfonso, Edginton, Andrea N., Blanchette, Victor, Blatny, Jan, Boban, Ana, Cnossen, Marjon, Collins, Peter, Croteau, Stacy E., Fischer, Katheljin, Hart, Daniel P., Ito, Shinya, Korth‐Bradley, Joan, Lethagen, Stefan, Lillicrap, David, Makris, Mike, Mathôt, Ron, Morfini, Massimo, Neufeld, Ellis J., Spears, Jeffrey
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Online‐only Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046594/ https://www.ncbi.nlm.nih.gov/pubmed/30046759 http://dx.doi.org/10.1002/rth2.12106

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