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Impact of the Variable Killer Ig-Like Receptor–Human Leukocyte Antigen Interactions on Natural Killer Cell Cytotoxicity Toward Foreign CD4 T Cells

BACKGROUND: Natural killer (NK) cells are known to mount a response against foreign target cells, where the absence of the dominant inhibitory killer Ig-like receptor (KIR)–human leukocyte antigen (HLA) interaction immensely lowers the threshold for NK cell activation. NK cells could thus constitute...

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Detalles Bibliográficos
Autores principales:	Hens, Jef, Goovaerts, Odin, Ceulemans, Ann, Jennes, Wim, Kestens, Luc
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046604/ https://www.ncbi.nlm.nih.gov/pubmed/30038628 http://dx.doi.org/10.3389/fimmu.2018.01588

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