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LonP1 Differently Modulates Mitochondrial Function and Bioenergetics of Primary Versus Metastatic Colon Cancer Cells

Mitochondrial Lon protease (LonP1) is a multi-function enzyme that regulates mitochondrial functions in several human malignancies, including colorectal cancer (CRC). The mechanism(s) by which LonP1 contributes to colorectal carcinogenesis is not fully understood. We found that silencing LonP1 leads...

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Detalles Bibliográficos
Autores principales:	Gibellini, Lara, Losi, Lorena, De Biasi, Sara, Nasi, Milena, Lo Tartaro, Domenico, Pecorini, Simone, Patergnani, Simone, Pinton, Paolo, De Gaetano, Anna, Carnevale, Gianluca, Pisciotta, Alessandra, Mariani, Francesco, Roncucci, Luca, Iannone, Anna, Cossarizza, Andrea, Pinti, Marcello
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046640/ https://www.ncbi.nlm.nih.gov/pubmed/30038898 http://dx.doi.org/10.3389/fonc.2018.00254

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