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S-adenosylhomocysteine hydrolase over-expression does not alter S-adenosylmethionine or S-adenosylhomocysteine levels in CBS deficient mice
Elevated plasma total homocysteine (tHcy) is associated with a number of human diseases including coronary artery disease, stroke, osteoporosis and dementia. It is highly correlated with intracellular S-adenosylhomocysteine (SAH). Since SAH is a strong inhibitor of methyl-transfer reactions involvin...
Autores principales: | Lee, Hyung-Ok, Wang, Liqun, Kuo, Yin-Ming, Andrews, Andrew J., Gupta, Sapna, Kruger, Warren D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047060/ https://www.ncbi.nlm.nih.gov/pubmed/30023284 http://dx.doi.org/10.1016/j.ymgmr.2018.01.002 |
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