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S-adenosylhomocysteine hydrolase over-expression does not alter S-adenosylmethionine or S-adenosylhomocysteine levels in CBS deficient mice

Elevated plasma total homocysteine (tHcy) is associated with a number of human diseases including coronary artery disease, stroke, osteoporosis and dementia. It is highly correlated with intracellular S-adenosylhomocysteine (SAH). Since SAH is a strong inhibitor of methyl-transfer reactions involvin...

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Detalles Bibliográficos
Autores principales:	Lee, Hyung-Ok, Wang, Liqun, Kuo, Yin-Ming, Andrews, Andrew J., Gupta, Sapna, Kruger, Warren D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047060/ https://www.ncbi.nlm.nih.gov/pubmed/30023284 http://dx.doi.org/10.1016/j.ymgmr.2018.01.002

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