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Effect of CD14/TLR4 antagonist on GnRH/LH secretion in ewe during central inflammation induced by intracerebroventricular administration of LPS

BACKGROUND: Immune stress induced by lipopolysaccharide (LPS) influences the gonadotropin-releasing hormone (GnRH)/luteinizing hormone (LH) secretion. Presence of LPS interacting Toll-like receptor (TLR) 4 in the hypothalamus may enable the direct action of LPS on the GnRH/LH secretion. So, the aim...

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Detalles Bibliográficos
Autores principales: Haziak, Karolina, Herman, Andrzej Przemysław, Wojtulewicz, Karolina, Pawlina, Bartosz, Paczesna, Kamila, Bochenek, Joanna, Tomaszewska-Zaremba, Dorota
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047126/
https://www.ncbi.nlm.nih.gov/pubmed/30026944
http://dx.doi.org/10.1186/s40104-018-0267-8

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