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Marked elevation in plasma trimethylamine-N-oxide (TMAO) in patients with mitochondrial disorders treated with oral l-carnitine

Oral supplementation with l-carnitine is a common therapeutic modality for mitochondrial disorders despite limited evidence of efficacy. Recently, a number of studies have demonstrated that a gut microbiota-dependent metabolite of l-carnitine, trimethylamine oxide (TMAO), is an independent and dose-...

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Detalles Bibliográficos
Autores principales:	Vallance, H.D., Koochin, A., Branov, J., Rosen-Heath, A., Bosdet, T., Wang, Z., Hazen, S.L., Horvath, G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047224/ https://www.ncbi.nlm.nih.gov/pubmed/30023305 http://dx.doi.org/10.1016/j.ymgmr.2018.04.005

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