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Transcriptional Changes in Cancer Cells Induced by Exposure to a Healing Method
Energy healing, or healing with intent, is a complementary and alternative medicine therapy reported to be beneficial with a wide variety of conditions. We are developing a delivery technology for a method previously tested in mouse models with solid tumors (the Bengston method) independent of the p...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047252/ https://www.ncbi.nlm.nih.gov/pubmed/30022894 http://dx.doi.org/10.1177/1559325818782843 |
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author | Beseme, Sarah Bengston, William Radin, Dean Turner, Michael McMichael, John |
author_facet | Beseme, Sarah Bengston, William Radin, Dean Turner, Michael McMichael, John |
author_sort | Beseme, Sarah |
collection | PubMed |
description | Energy healing, or healing with intent, is a complementary and alternative medicine therapy reported to be beneficial with a wide variety of conditions. We are developing a delivery technology for a method previously tested in mouse models with solid tumors (the Bengston method) independent of the presence of a healer. The goal of this study was to assess whether stored or recorded energy has an impact on breast cancer cells in vitro, using energy-charged cotton and electromagnetic recording of healers practicing the method. Expression of genes involved in cancer and inflammation pathways was measured by quantitative reverse transcription polymerase chain reaction (qRT-PCR). Treatment of cells using energy-charged cotton resulted in statistically significant changes <1.5-fold. In cells exposed to an electromagnetic recording, 37 genes of 167 tested showed a >1.5-fold change when compared to the control, and 68 genes showing statistically significant fold changes. Two genes, ATP citrate lyase (ACLY) and interleukin 1β (IL-1β), were consistently downregulated at 4 and 24 hours of exposure to the recording, respectively, in 3 independent experiments. Both ACLY and IL-1β were also downregulated in cells exposed to a hands-on delivery of the method, suggesting these 2 genes as potential markers of the healing method. |
format | Online Article Text |
id | pubmed-6047252 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-60472522018-07-18 Transcriptional Changes in Cancer Cells Induced by Exposure to a Healing Method Beseme, Sarah Bengston, William Radin, Dean Turner, Michael McMichael, John Dose Response Original Article Energy healing, or healing with intent, is a complementary and alternative medicine therapy reported to be beneficial with a wide variety of conditions. We are developing a delivery technology for a method previously tested in mouse models with solid tumors (the Bengston method) independent of the presence of a healer. The goal of this study was to assess whether stored or recorded energy has an impact on breast cancer cells in vitro, using energy-charged cotton and electromagnetic recording of healers practicing the method. Expression of genes involved in cancer and inflammation pathways was measured by quantitative reverse transcription polymerase chain reaction (qRT-PCR). Treatment of cells using energy-charged cotton resulted in statistically significant changes <1.5-fold. In cells exposed to an electromagnetic recording, 37 genes of 167 tested showed a >1.5-fold change when compared to the control, and 68 genes showing statistically significant fold changes. Two genes, ATP citrate lyase (ACLY) and interleukin 1β (IL-1β), were consistently downregulated at 4 and 24 hours of exposure to the recording, respectively, in 3 independent experiments. Both ACLY and IL-1β were also downregulated in cells exposed to a hands-on delivery of the method, suggesting these 2 genes as potential markers of the healing method. SAGE Publications 2018-07-11 /pmc/articles/PMC6047252/ /pubmed/30022894 http://dx.doi.org/10.1177/1559325818782843 Text en © The Author(s) 2018 http://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Original Article Beseme, Sarah Bengston, William Radin, Dean Turner, Michael McMichael, John Transcriptional Changes in Cancer Cells Induced by Exposure to a Healing Method |
title | Transcriptional Changes in Cancer Cells Induced by Exposure to a
Healing Method |
title_full | Transcriptional Changes in Cancer Cells Induced by Exposure to a
Healing Method |
title_fullStr | Transcriptional Changes in Cancer Cells Induced by Exposure to a
Healing Method |
title_full_unstemmed | Transcriptional Changes in Cancer Cells Induced by Exposure to a
Healing Method |
title_short | Transcriptional Changes in Cancer Cells Induced by Exposure to a
Healing Method |
title_sort | transcriptional changes in cancer cells induced by exposure to a
healing method |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047252/ https://www.ncbi.nlm.nih.gov/pubmed/30022894 http://dx.doi.org/10.1177/1559325818782843 |
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