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Age-related Beta-synuclein Alters the p53/Mdm2 Pathway and Induces the Apoptosis of Brain Microvascular Endothelial Cells In Vitro

Increased β-synuclein (Sncb) expression has been described in the aging visual system. Sncb functions as the physiological antagonist of α-synuclein (Snca), which is involved in the development of neurodegenerative diseases, such as Parkinson’s and Alzheimer’s diseases. However, the exact function o...

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Detalles Bibliográficos
Autores principales:	Brockhaus, Katrin, Böhm, Michael R. R., Melkonyan, Harutyun, Thanos, Solon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2018
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047277/ https://www.ncbi.nlm.nih.gov/pubmed/29808713 http://dx.doi.org/10.1177/0963689718755706

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