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A somatic mutation in erythro-myeloid progenitors causes neurodegenerative disease

The pathophysiology of neurodegenerative diseases is poorly understood, and therapeutic options are few. Neurodegenerative diseases are hallmarked by progressive neuronal dysfunction and loss, associated with chronic glial activation(1). Whether microglial activation, which is viewed in general as a...

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Detalles Bibliográficos
Autores principales: Mass, Elvira, Jacome-Galarza, Christian E., Blank, Thomas, Lazarov, Tomi, Durham, Benjamin H., Ozkaya, Neval, Pastore, Alessandro, Schwabenland, Marius, Chung, Young Rock, Rosenblum, Marc K., Prinz, Marco, Abdel-Wahab, Omar, Geissmann, Frederic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047345/
https://www.ncbi.nlm.nih.gov/pubmed/28854169
http://dx.doi.org/10.1038/nature23672