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A somatic mutation in erythro-myeloid progenitors causes neurodegenerative disease
The pathophysiology of neurodegenerative diseases is poorly understood, and therapeutic options are few. Neurodegenerative diseases are hallmarked by progressive neuronal dysfunction and loss, associated with chronic glial activation(1). Whether microglial activation, which is viewed in general as a...
Autores principales: | Mass, Elvira, Jacome-Galarza, Christian E., Blank, Thomas, Lazarov, Tomi, Durham, Benjamin H., Ozkaya, Neval, Pastore, Alessandro, Schwabenland, Marius, Chung, Young Rock, Rosenblum, Marc K., Prinz, Marco, Abdel-Wahab, Omar, Geissmann, Frederic |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047345/ https://www.ncbi.nlm.nih.gov/pubmed/28854169 http://dx.doi.org/10.1038/nature23672 |
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