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RabGTD: a comprehensive database of rabbit genome and transcriptome
The rabbit is a very important species for both biomedical research and agriculture animal breeding. They are not only the most-used experimental animals for the production of antibodies, but also widely used for studying a variety of human diseases. Here we developed RabGTD, the first comprehensive...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047408/ https://www.ncbi.nlm.nih.gov/pubmed/30010730 http://dx.doi.org/10.1093/database/bay075 |
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author | Zhou, Lu Xiao, Qingyu Bi, Jie Wang, Zhen Li, Yixue |
author_facet | Zhou, Lu Xiao, Qingyu Bi, Jie Wang, Zhen Li, Yixue |
author_sort | Zhou, Lu |
collection | PubMed |
description | The rabbit is a very important species for both biomedical research and agriculture animal breeding. They are not only the most-used experimental animals for the production of antibodies, but also widely used for studying a variety of human diseases. Here we developed RabGTD, the first comprehensive rabbit database containing both genome and transcriptome data generated by next-generation sequencing. Genomic variations coming from 79 samples were identified and annotated, including 33 samples of wild rabbits and 46 samples of domestic rabbits with diverse populations. Gene expression profiles of 86 tissue samples were complied, including those from the most commonly used models for hyperlipidemia and atherosclerosis. RabGTD is a web-based and open-access resource, which also provides convenient functions and friendly interfaces of searching, browsing and downloading for users to explore the big data. Database URL: http://www.picb.ac.cn/RabGTD/ |
format | Online Article Text |
id | pubmed-6047408 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-60474082018-07-19 RabGTD: a comprehensive database of rabbit genome and transcriptome Zhou, Lu Xiao, Qingyu Bi, Jie Wang, Zhen Li, Yixue Database (Oxford) Database Tool The rabbit is a very important species for both biomedical research and agriculture animal breeding. They are not only the most-used experimental animals for the production of antibodies, but also widely used for studying a variety of human diseases. Here we developed RabGTD, the first comprehensive rabbit database containing both genome and transcriptome data generated by next-generation sequencing. Genomic variations coming from 79 samples were identified and annotated, including 33 samples of wild rabbits and 46 samples of domestic rabbits with diverse populations. Gene expression profiles of 86 tissue samples were complied, including those from the most commonly used models for hyperlipidemia and atherosclerosis. RabGTD is a web-based and open-access resource, which also provides convenient functions and friendly interfaces of searching, browsing and downloading for users to explore the big data. Database URL: http://www.picb.ac.cn/RabGTD/ Oxford University Press 2018-07-13 /pmc/articles/PMC6047408/ /pubmed/30010730 http://dx.doi.org/10.1093/database/bay075 Text en © The Author(s) 2018. Published by Oxford University Press. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Database Tool Zhou, Lu Xiao, Qingyu Bi, Jie Wang, Zhen Li, Yixue RabGTD: a comprehensive database of rabbit genome and transcriptome |
title | RabGTD: a comprehensive database of rabbit genome and transcriptome |
title_full | RabGTD: a comprehensive database of rabbit genome and transcriptome |
title_fullStr | RabGTD: a comprehensive database of rabbit genome and transcriptome |
title_full_unstemmed | RabGTD: a comprehensive database of rabbit genome and transcriptome |
title_short | RabGTD: a comprehensive database of rabbit genome and transcriptome |
title_sort | rabgtd: a comprehensive database of rabbit genome and transcriptome |
topic | Database Tool |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047408/ https://www.ncbi.nlm.nih.gov/pubmed/30010730 http://dx.doi.org/10.1093/database/bay075 |
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