Endothelial Insulin Receptor Restoration Rescues Vascular Function in Male Insulin Receptor Haploinsufficient Mice

Reduced systemic insulin signaling promotes endothelial dysfunction and diminished endogenous vascular repair. We investigated whether restoration of endothelial insulin receptor expression could rescue this phenotype. Insulin receptor knockout (IRKO) mice were crossed with mice expressing a human i...

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Detalles Bibliográficos
Autores principales: Sengupta, Anshuman, Patel, Peysh A, Yuldasheva, Nadira Y, Mughal, Romana S, Galloway, Stacey, Viswambharan, Hema, Walker, Andrew M N, Aziz, Amir, Smith, Jessica, Ali, Noman, Mercer, Ben N, Imrie, Helen, Sukumar, Piruthivi, Wheatcroft, Stephen B, Kearney, Mark T, Cubbon, Richard M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047419/
https://www.ncbi.nlm.nih.gov/pubmed/29796592
http://dx.doi.org/10.1210/en.2018-00215

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047419/
https://www.ncbi.nlm.nih.gov/pubmed/29796592
http://dx.doi.org/10.1210/en.2018-00215

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