Susceptibility of low-density lipoprotein particles to aggregate depends on particle lipidome, is modifiable, and associates with future cardiovascular deaths

AIMS: Low-density lipoprotein (LDL) particles cause atherosclerotic cardiovascular disease (ASCVD) through their retention, modification, and accumulation within the arterial intima. High plasma concentrations of LDL drive this disease, but LDL quality may also contribute. Here, we focused on the in...

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Detalles Bibliográficos
Autores principales: Ruuth, Maija, Nguyen, Su Duy, Vihervaara, Terhi, Hilvo, Mika, Laajala, Teemu D, Kondadi, Pradeep Kumar, Gisterå, Anton, Lähteenmäki, Hanna, Kittilä, Tiia, Huusko, Jenni, Uusitupa, Matti, Schwab, Ursula, Savolainen, Markku J, Sinisalo, Juha, Lokki, Marja-Liisa, Nieminen, Markku S, Jula, Antti, Perola, Markus, Ylä-Herttula, Seppo, Rudel, Lawrence, Öörni, Anssi, Baumann, Marc, Baruch, Amos, Laaksonen, Reijo, Ketelhuth, Daniel F J, Aittokallio, Tero, Jauhiainen, Matti, Käkelä, Reijo, Borén, Jan, Williams, Kevin Jon, Kovanen, Petri T, Öörni, Katariina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Basic Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047440/
https://www.ncbi.nlm.nih.gov/pubmed/29982602
http://dx.doi.org/10.1093/eurheartj/ehy319

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