A Case of Annular Elastolytic Giant Cell Granuloma Associated with Syphilis

Annular elastolytic giant cell granuloma (AEGCG) is a rare granulomatous skin disease characterized by annular patches with slightly raised borders, hypopigmented and/or atrophic centers found mainly on sun-exposed skin. Histologically, it is characterized by phagocytosis of elastic fibers by multin...

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Detalles Bibliográficos
Autores principales: Liu, Xiaoping, Zhang, Wei, Liu, Yeqiang, Xu, Mingyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2018
Materias:
Single Case
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047546/
https://www.ncbi.nlm.nih.gov/pubmed/30022935
http://dx.doi.org/10.1159/000489910
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author Liu, Xiaoping
Zhang, Wei
Liu, Yeqiang
Xu, Mingyuan
author_facet Liu, Xiaoping
Zhang, Wei
Liu, Yeqiang
Xu, Mingyuan
author_sort Liu, Xiaoping
collection PubMed
description Annular elastolytic giant cell granuloma (AEGCG) is a rare granulomatous skin disease characterized by annular patches with slightly raised borders, hypopigmented and/or atrophic centers found mainly on sun-exposed skin. Histologically, it is characterized by phagocytosis of elastic fibers by multinucleated giant cells. The pathogenesis of the disease is unclear. We report a case of 55-year-old man with AEGCG in association with syphilis, whose condition improved when hydroxychloroquine sulfate and topical tacrolimus were administered over a 2-month period.
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spelling pubmed-60475462018-07-18 A Case of Annular Elastolytic Giant Cell Granuloma Associated with Syphilis Liu, Xiaoping Zhang, Wei Liu, Yeqiang Xu, Mingyuan Case Rep Dermatol Single Case Annular elastolytic giant cell granuloma (AEGCG) is a rare granulomatous skin disease characterized by annular patches with slightly raised borders, hypopigmented and/or atrophic centers found mainly on sun-exposed skin. Histologically, it is characterized by phagocytosis of elastic fibers by multinucleated giant cells. The pathogenesis of the disease is unclear. We report a case of 55-year-old man with AEGCG in association with syphilis, whose condition improved when hydroxychloroquine sulfate and topical tacrolimus were administered over a 2-month period. S. Karger AG 2018-06-05 /pmc/articles/PMC6047546/ /pubmed/30022935 http://dx.doi.org/10.1159/000489910 Text en Copyright © 2018 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/4.0/ This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Single Case
Liu, Xiaoping
Zhang, Wei
Liu, Yeqiang
Xu, Mingyuan
A Case of Annular Elastolytic Giant Cell Granuloma Associated with Syphilis
title A Case of Annular Elastolytic Giant Cell Granuloma Associated with Syphilis
title_full A Case of Annular Elastolytic Giant Cell Granuloma Associated with Syphilis
title_fullStr A Case of Annular Elastolytic Giant Cell Granuloma Associated with Syphilis
title_full_unstemmed A Case of Annular Elastolytic Giant Cell Granuloma Associated with Syphilis
title_short A Case of Annular Elastolytic Giant Cell Granuloma Associated with Syphilis
title_sort case of annular elastolytic giant cell granuloma associated with syphilis
topic Single Case
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047546/
https://www.ncbi.nlm.nih.gov/pubmed/30022935
http://dx.doi.org/10.1159/000489910
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