Mixed Neuroendocrine Carcinoma and Squamous Cell Carcinoma of the Colon: Case Report and Literature Review

Neuroendocrine carcinoma (NEC) of the colon is very rare, and squamous cell carcinoma (SCC) of colon cancer is rare. We recently treated a patient with both NEC and SCC that initially presented as multiple unresectable liver and lung metastases. A 68-year-old Japanese man was referred to our hospita...

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Detalles Bibliográficos
Autores principales: Munakata, Shinya, Murai, Yuta, Koizumi, Akihiro, Kato, Hisaki, Yamamoto, Riku, Ueda, Shuhei, Tokuda, Satoshi, Sakuraba, Shunsuke, Kushida, Tomoyuki, Orita, Hajime, Sakurada, Mutsumi, Maekawa, Hiroshi, Sato, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2018
Materias:
Single Case
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047564/
https://www.ncbi.nlm.nih.gov/pubmed/30022911
http://dx.doi.org/10.1159/000488194
Descripción
Sumario:Neuroendocrine carcinoma (NEC) of the colon is very rare, and squamous cell carcinoma (SCC) of colon cancer is rare. We recently treated a patient with both NEC and SCC that initially presented as multiple unresectable liver and lung metastases. A 68-year-old Japanese man was referred to our hospital because of diarrhea with descending colon cancer obstruction. He underwent a left colectomy. Based on immunohistochemistry results, we diagnosed mixed NEC and SCC, the primary lesion location of which was probably the lung in the final pathologic examination. He began systemic palliative chemotherapy with CDDP and CPT-11. After 3 months of treatment, shown the progressive disease, we started CDDP and VP-16. The patient was not eligible for additional chemotherapy after 2 months.

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