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Pulmonary Fat Embolism and Coronary Amyloidosis

Patient: Male, 72 Final Diagnosis: Fat lung embolism Symptoms: Dyspnea Medication: — Clinical Procedure: — Specialty: Orthpedics and Traumatology OBJECTIVE: Diagnostic/therapeutic accidents BACKGROUND: Fat embolism syndrome is a well-known complication in orthopedic and trauma surgery, caused by a m...

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Autores principales: Lever, Veronica, Erdini, Francesco, Ghimenton, Claudio, Novelli, Luca, Brunelli, Matteo, Barbareschi, Mattia, Mazzoleni, Guido, Vermiglio, Elisa, Mantovani, Alessandro, Cima, Luca, Valotto, Giovanni, Eccher, Albino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047570/
https://www.ncbi.nlm.nih.gov/pubmed/29937538
http://dx.doi.org/10.12659/AJCR.908561
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author Lever, Veronica
Erdini, Francesco
Ghimenton, Claudio
Novelli, Luca
Brunelli, Matteo
Barbareschi, Mattia
Mazzoleni, Guido
Vermiglio, Elisa
Mantovani, Alessandro
Cima, Luca
Valotto, Giovanni
Eccher, Albino
author_facet Lever, Veronica
Erdini, Francesco
Ghimenton, Claudio
Novelli, Luca
Brunelli, Matteo
Barbareschi, Mattia
Mazzoleni, Guido
Vermiglio, Elisa
Mantovani, Alessandro
Cima, Luca
Valotto, Giovanni
Eccher, Albino
author_sort Lever, Veronica
collection PubMed
description Patient: Male, 72 Final Diagnosis: Fat lung embolism Symptoms: Dyspnea Medication: — Clinical Procedure: — Specialty: Orthpedics and Traumatology OBJECTIVE: Diagnostic/therapeutic accidents BACKGROUND: Fat embolism syndrome is a well-known complication in orthopedic and trauma surgery, caused by a massive release of fat into the circulation that can lead to cardiopulmonary insufficiency and multiorgan failure. CASE REPORT: We present the case of a 72-year-old man with osteoarthritis who underwent an elective right cementless total hip arthroplasty. Two hours after surgery, the patient lost consciousness and was found hypotensive and with reduced oxygen saturation, with a severe right heart dilatation at echocardiographic evaluation. Death occurred after cardiopulmonary resuscitation attempts. Post-mortem microscopic examination revealed that the final cause of death was pulmonary fat embolism associated with coronary amyloidosis and atherosclerosis. CONCLUSIONS: This case called our attention on the sudden onset of fat embolism syndrome after arthroplasty and the insidious nature of amyloidosis infiltrative disease. The autopsy findings substantially aided understanding the immediate cause of death.
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spelling pubmed-60475702018-07-18 Pulmonary Fat Embolism and Coronary Amyloidosis Lever, Veronica Erdini, Francesco Ghimenton, Claudio Novelli, Luca Brunelli, Matteo Barbareschi, Mattia Mazzoleni, Guido Vermiglio, Elisa Mantovani, Alessandro Cima, Luca Valotto, Giovanni Eccher, Albino Am J Case Rep Articles Patient: Male, 72 Final Diagnosis: Fat lung embolism Symptoms: Dyspnea Medication: — Clinical Procedure: — Specialty: Orthpedics and Traumatology OBJECTIVE: Diagnostic/therapeutic accidents BACKGROUND: Fat embolism syndrome is a well-known complication in orthopedic and trauma surgery, caused by a massive release of fat into the circulation that can lead to cardiopulmonary insufficiency and multiorgan failure. CASE REPORT: We present the case of a 72-year-old man with osteoarthritis who underwent an elective right cementless total hip arthroplasty. Two hours after surgery, the patient lost consciousness and was found hypotensive and with reduced oxygen saturation, with a severe right heart dilatation at echocardiographic evaluation. Death occurred after cardiopulmonary resuscitation attempts. Post-mortem microscopic examination revealed that the final cause of death was pulmonary fat embolism associated with coronary amyloidosis and atherosclerosis. CONCLUSIONS: This case called our attention on the sudden onset of fat embolism syndrome after arthroplasty and the insidious nature of amyloidosis infiltrative disease. The autopsy findings substantially aided understanding the immediate cause of death. International Scientific Literature, Inc. 2018-06-25 /pmc/articles/PMC6047570/ /pubmed/29937538 http://dx.doi.org/10.12659/AJCR.908561 Text en © Am J Case Rep, 2018 This work is licensed under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) )
spellingShingle Articles
Lever, Veronica
Erdini, Francesco
Ghimenton, Claudio
Novelli, Luca
Brunelli, Matteo
Barbareschi, Mattia
Mazzoleni, Guido
Vermiglio, Elisa
Mantovani, Alessandro
Cima, Luca
Valotto, Giovanni
Eccher, Albino
Pulmonary Fat Embolism and Coronary Amyloidosis
title Pulmonary Fat Embolism and Coronary Amyloidosis
title_full Pulmonary Fat Embolism and Coronary Amyloidosis
title_fullStr Pulmonary Fat Embolism and Coronary Amyloidosis
title_full_unstemmed Pulmonary Fat Embolism and Coronary Amyloidosis
title_short Pulmonary Fat Embolism and Coronary Amyloidosis
title_sort pulmonary fat embolism and coronary amyloidosis
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047570/
https://www.ncbi.nlm.nih.gov/pubmed/29937538
http://dx.doi.org/10.12659/AJCR.908561
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