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Emodin mitigates podocytes apoptosis induced by endoplasmic reticulum stress through the inhibition of the PERK pathway in diabetic nephropathy

BACKGROUND: Endoplasmic reticulum stress is associated with podocyte apoptosis in the pathogenesis of diabetic nephropathy (DN). A previous study has demonstrated that emodin has a protective effect in the kidney by suppressing proliferation of mesangial cells and inhibiting the renal tubular epithe...

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Detalles Bibliográficos
Autores principales:	Tian, Nianxiu, Gao, Yanbin, Wang, Xiaolei, Wu, Xiaoming, Zou, Dawei, Zhu, Zhiyao, Han, ZheJi, Wang, Tao, Shi, Yimin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047613/ https://www.ncbi.nlm.nih.gov/pubmed/30034224 http://dx.doi.org/10.2147/DDDT.S167405

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