Cargando…

The TGFα-EGFR-Akt signaling axis plays a role in enhancing proinflammatory chemokines in triple-negative breast cancer cells

Triple-negative breast cancer (TNBC) is aggressive and typically has a poor prognosis. Chemokines have chemoattractant potential for cancer metastasis. Here, we investigated the chemokine signatures in BC subtypes and the underlying mechanisms that enhance proinflammatory chemokines in TNBC. Analysi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ignacio, Rosa Mistica C., Gibbs, Carla R., Lee, Eun-Sook, Son, Deok-Soo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047672/ https://www.ncbi.nlm.nih.gov/pubmed/30034618 http://dx.doi.org/10.18632/oncotarget.25389

Ejemplares similares

Differential Chemokine Signature between Human Preadipocytes and Adipocytes
por: Ignacio, Rosa Mistica C., et al.
Publicado: (2016)

Serum amyloid A predisposes inflammatory tumor microenvironment in triple negative breast cancer
por: Ignacio, Rosa Mistica C., et al.
Publicado: (2019)

Potential Roles of Innate Immune Chemokine and Cytokine Network on Lipopolysaccharide-Based Therapeutic Approach in Ovarian Cancer
por: Ignacio, Rosa Mistica C., et al.
Publicado: (2019)

CXCR2-Driven Ovarian Cancer Progression Involves Upregulation of Proinflammatory Chemokines by Potentiating NF-κB Activation via EGFR-Transactivated Akt Signaling
por: Dong, Yuan-Lin, et al.
Publicado: (2013)

Chemokine Network and Overall Survival in TP53 Wild-Type and Mutant Ovarian Cancer
por: Ignacio, Rosa Mistica C., et al.
Publicado: (2018)

Chemokine network during adipogenesis in 3T3-L1 cells: Differential response between growth and proinflammatory factor in preadipocytes vs. adipocytes
por: Kabir, Syeda M, et al.
Publicado: (2014)

CXCR2 is a negative regulator of p21 in p53-dependent and independent manner via Akt-mediated Mdm2 in ovarian cancer
por: Ignacio, Rosa Mistica C., et al.
Publicado: (2018)

NF-κB-Mediated CCL20 Reigns Dominantly in CXCR2-Driven Ovarian Cancer Progression
por: Ignacio, Rosa Mistica C., et al.
Publicado: (2016)

Augmented Serum Amyloid A1/2 Mediated by TNF-induced NF-κB in Human Serous Ovarian Epithelial Tumors
por: Choi, Hyeongjwa, et al.
Publicado: (2017)

Localization of Serum Amyloid A3 in the Mouse Ovary
por: Choi, Hyeongjwa, et al.
Publicado: (2017)

Obesity-Induced Peritoneal Dissemination of Ovarian Cancer and Dominant Recruitment of Macrophages in Ascites
por: Ignacio, Rosa Mistica C., et al.
Publicado: (2018)

Inhibitory Effect of Tumor Suppressor p53 on Proinflammatory Chemokine Expression in Ovarian Cancer Cells by Reducing Proteasomal Degradation of IκB
por: Son, Deok-Soo, et al.
Publicado: (2012)

Follicular Proinflammatory Cytokines and Chemokines as Markers of IVF Success
por: Sarapik, Aili, et al.
Publicado: (2012)

The Associations between Infertility and Antioxidants, Proinflammatory Cytokines, and Chemokines
por: Chyra-Jach, Dorota, et al.
Publicado: (2018)

CXCL14 Attenuates Triple-Negative Breast Cancer Progression by Regulating Immune Profiles of the Tumor Microenvironment in a T Cell-Dependent Manner
por: Gibbs, Carla, et al.
Publicado: (2022)

cIAP1 regulates the EGFR/Snai2 axis in triple-negative breast cancer cells
por: Majorini, Maria Teresa, et al.
Publicado: (2018)

Proinflammatory Cytokines and Chemokines at the Skin Interface during Powassan Virus Transmission
por: Hermance, Meghan E, et al.
Publicado: (2014)

Evaluation of Proinflammatory Chemokines in HIV Patients with Asymptomatic Leishmania Infantum Infection
por: Monteiro, Bruna Eduarda Freitas, et al.
Publicado: (2023)

Targeting EGFR in Triple Negative Breast Cancer
por: Ueno, Naoto T., et al.
Publicado: (2011)

TGF-β Signaling in Cancer: Control by Negative Regulators and Crosstalk with Proinflammatory and Fibrogenic Pathways
por: Ungefroren, Hendrik
Publicado: (2019)

MicroRNA-34a/EGFR axis plays pivotal roles in lung tumorigenesis
por: Li, Y-L, et al.
Publicado: (2017)

Proinflammatory Markers, Chemokines, and Enkephalin in Patients Suffering from Dry Eye Disease
por: Nicolle, Pierre, et al.
Publicado: (2018)

Single cell analysis reveals satellite cell heterogeneity for proinflammatory chemokine expression
por: Andre, Alexander B., et al.
Publicado: (2023)

MYD88 and Proinflammatory Chemokines in Aortic Atheromatosis: Exploring Novel Statin Effects
por: Mylonas, Konstantinos S., et al.
Publicado: (2023)

Inhibition of the PI3K/AKT pathway potentiates cytotoxicity of EGFR kinase inhibitors in triple-negative breast cancer cells
por: Yi, Yong Weon, et al.
Publicado: (2013)

Protein Tyrosine Kinase 7 Regulates EGFR/Akt Signaling Pathway and Correlates With Malignant Progression in Triple-Negative Breast Cancer
por: Cui, Nai-Peng, et al.
Publicado: (2021)

Triple negative breast carcinoma EGFR amplification is not associated with EGFR, Kras or ALK mutations
por: Secq, V, et al.
Publicado: (2014)

Korean Red Ginseng improves atopic dermatitis-like skin lesions by suppressing expression of proinflammatory cytokines and chemokines in vivo and in vitro
por: Kee, Ji-Ye, et al.
Publicado: (2017)

Playing With Fire: Proinflammatory Virulence Mechanisms of Group A Streptococcus
por: Wilde, Shyra, et al.
Publicado: (2021)

Inhibition of EGFR-AKT Axis Results in the Suppression of Ovarian Tumors In Vitro and in Preclinical Mouse Model
por: Loganathan, Sivakumar, et al.
Publicado: (2012)

Triple therapy with osimertinib, bevacizumab and cetuximab in EGFR-mutant lung cancer with HIF-1α/TGF-α expression
por: Nishii, Kazuya, et al.
Publicado: (2021)

Advanced Glycation End Products Play Adverse Proinflammatory Activities in Osteoporosis
por: Sanguineti, Roberta, et al.
Publicado: (2014)

ProNGF-p75NTR axis plays a proinflammatory role in inflamed joints: a novel pathogenic mechanism in chronic arthritis
por: Minnone, Gaetana, et al.
Publicado: (2017)

Excessive proinflammatory cytokine and chemokine responses of human monocyte-derived macrophages to enterovirus 71 infection
por: Gong, Xun, et al.
Publicado: (2012)

Characteristics of Proinflammatory Cytokines and Chemokines in Airways of Asthmatics: Relationships with Disease Severity and Infiltration of Inflammatory Cells
por: Yang, Ting, et al.
Publicado: (2017)

Akt3 promotes cancer stemness in triple-negative breast cancer through YB1-Snail/Slug signaling axis
por: Tian, Ye, et al.
Publicado: (2022)

Endoglin Modulates TGFβR2 Induced VEGF and Proinflammatory Cytokine Axis Mediated Angiogenesis in Prolonged DEHP-Exposed Breast Cancer Cells
por: Jadhao, Mahendra, et al.
Publicado: (2022)

SKA3 promotes lung adenocarcinoma metastasis through the EGFR–PI3K–Akt axis
por: Hu, Dan-dan, et al.
Publicado: (2020)

Targeting MET and EGFR crosstalk signaling in triple-negative breast cancers
por: Linklater, Erik S., et al.
Publicado: (2016)

Expression and clinical significance of MAPK and EGFR in triple-negative breast cancer
por: Jiang, Weihua, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_a2mqmt5n9utkb3541pgrle7n1p